HIV 1/2 Test

The ADEXUSDx® HIV-1/2 Antibody Test is an immunochromatographic assay used for the qualitative detection of antibodies against human immunodeficiency virus (HIV) in human whole blood, plasma or serum samples. Human immunodeficiency virus is a slow replicating retrovirus that causes acquired immunodeficiency syndrome (AIDS). HIV-1 is more prevalent worldwide; however, HIV-2 has not been widely seen outside of Africa. There are a number of tests that are used to determine whether a person is infected with HIV. These include the HIV antibody test, P24 antigen test and PCR test for HIV RNA or DNA. There are other tests that are used to measure the severity or monitor therapy of HIV infection such as CD4 count and the viral load test. HIV antibody detection based rapid test is the most appropriate test for routine diagnosis of HIV infection among adults. Most people develop detectable HIV antibodies with 6 to 12 weeks of infection. Due to structural similarity between HIV-1 and HIV-2 antigens, HIV-1/2 Antibody Test cannot discriminate between HIV-1 and HIV-2 infection.

Human immunodeficiency virus is a slow replicating retrovirus that causes acquired immunodeficiency syndrome (AIDS). HIV-1 is more prevalent within North America and in most other regions worldwide. However, HIV2 has not been widely seen outside of Africa. There are a number of tests that are used to determine whether a person is infected with HIV. These include the HIV antibody test, P24 antigen test and PCR test for HIV RNA or DNA. There are other tests that are used to measure the severity or monitor therapy of HIV infection such as CD4 count and the viral load test. HIV antibody detection based rapid test is the most appropriate test for routine diagnosis of HIV infection among adults. Most people develop detectable HIV antibodies within 6 to 12 weeks of infection. The ‘window period’ is a term used to describe the period of time between HIV infection and the production of antibodies. During this time, an antibody test may give a ‘false negative’ result for HIV infection, which means the test will be negative, even though a person is infected with HIV.

The ADEXUSDx® HIV-1/2 Antibody Test is a one-step rapid chromatographic double antigen sandwich immunoassay for whole blood, plasma or serum. When the sample in the Receiving Channel reaches the Fill Line, it first passes through a plasma separating membrane that traps red blood cells and contains HIV detector antigens derived from both HIV-1 and HIV-2. HIV antibodies in the sample bind to detector antigens to form coloured complexes. The coloured complexes migrate towards the test window and are immobilized in the Test Window Region of the analytical membrane by the HIV-1 antigen and/or HIV-2 antigen at the test band regions. The appearance of at least one visible red band at the test region indicates that the sample contains a detectable level of HIV antibodies. Due to structural similarity between HIV-1 and HIV-2 antigens, the ADEXUSDx® HIV-1/2 Antibody Test cannot discriminate between HIV-1 and HIV-2 infection.

Time to Result: 15 minutes
Result Window: 15-30 minutes
Storage Conditions: 4 ℃ – 25℃ (39℉ – 77℉ ) *Tests do not require refrigeration
Operating Temperature: 4 ℃ – 25℃ (39℉ – 77℉ ) *Tests do not require refrigeration
Test Shelf Life: 15 months- expiration dates printed on test pouches
Sample Type(s:): Capillary blood/whole blood/plasma/serum